Device Companies
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3Ti (Transfusion & Transplantation Technologies, Inc.)
Current Status: 3Ti is no longer in business.
Company Profile: Transfusion & Transplantation Technologies (3Ti) was developing novel automated blood testing instrumentation and associated consumables and services for the pre-transfusion (immunohematology) market worldwide. The initial product, the Aegis Blood Analyzer and System, was being designed to perform highly accurate, rapid and cost-effective blood grouping (ABO and Rh), red cell antibody screening/identification and certain donor/recipient cross-matching tests, all with walk-away automation. The Aegis System was being developd to perform 1) a full menu of routine blood bank tests; 2) certain tests that have still remained "un-automatable" on today's automated platforms (e.g., rWBC); and 3) potentially new and emerging tests and/or testing platforms going forward.
Affiliation to Emory: Christopher D. Hillyer, MD, (pathology) and John D. Roback, MD, PhD (pathology) were a co-founders.
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APICA Cardiovascular Technologies
Current Status: Apica Cardiovascular was acquired by Thoratec in 2014 and Thoratec was acquired by Abbott Laboratories in 2017.
Company Profile: Apica Cardiovascular simplifies cardiovascular surgery with its innovative closure port technology. Typically when a patient undergoes heart surgery, they must undergo cardiopulmonary bypass and have an invasive procedure performed for a lengthy period of time. With Apica Cardiovascular's technology, an easy access port is incorporated into the procedure and with it, a surgeon can deliver a cardio medical device straight to the beating heart without the loss of blood. After surgery, this port can still be accessed for future operations. This device technology not only improves the ease of surgery but greatly increases the safety of heart surgery for a patient.
Affiliation with Emory: Vinod Thourani, MD (cardiology & surgery) and Thomas Vassiliades, MD (surgery) are inventors.
Atrionix, Inc.
Current Status: Atrionix was acquired by Johnson & Johnson in 2000. J&J no longer has a license to Emory technology.
Company Profile: Atrionix developed and manufactured products for the diagnosis and treatment of atrial fibrillation, the most prevalent cardiac arrhythmia. During atrial fibrillation, the heart's two small upper chambers quiver instead of beating effectively. As a result, blood is not pumped completely out of the atria, so it may pool and clot, which could result in a stroke. The company developed several patented cardiac ablation medical devices that will eliminate the need for surgical intervention during the treatment of atrial fibrillation. These minimally invasive devices reduce patient morbidity and recovery time compared to surgical techniques.
Affiliation with Emory: Jonathan Langberg, MD (cardiology) is an inventor.
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BioSequent, LLC
Current Status: BioSequent is no longer in business.
Company Profile: BioSequent was developing biomaterials, devices, and pharmaceuticals for cardiovascular applications. The company's core technology is designed for the surgical treatment of both peripheral and coronary vascular diseases. It consists of elastin-mimetic protein triblock copolymers that can be formulated into synthetic bypass grafts. Initial studies showed that BioSequent's synthetic bypass grafts could overcome the size limitation and other technical issues of other products.
Affiliation with Emory: Elliot Chaikof, MD, PhD (surgery) and Vincent Conticello, PhD (chemistry) were scientific founders.
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Camerad Technologies, LLC
Address: 2098 Sylvania Drive, Decatur, GA 30033
Camerad website
CEO: Srini Tridandapani (CMO)
Current Status: In clinical validation
Company Profile: Camerad Technologies is developing the PatCam™ system which automatically adds point-of-care patient photos, reconnects the radiologist and patient, and reduces misidentification errors. The PatCam™ system incorporates digital cameras within medical imaging equipment and allows simultaneously acquisition, transmission, storage and retrieval of patient facial photographs along with medical imaging studies. The facial photograph acts as a unique, intrinsic, but externally visible patient identifier and can thus lead to detection of wrong-patient errors. Camerad™ Technologies' product development has been funded by the Georgia Research Alliance, the Coulter Translational Partnership, and federal government's Small Business Innovation Research (SBIR) grants.
Affiliation with Emory: Srini Tridandapani, MD, PhD (radiology) is a scientific co-founder. James Provenzale, MD, (radiology) Mo Salama, MS, (Emory Clinic) and Senthil Ramamurthy, MSEE (radiology) are co-inventors.
Cyberkinetics Neurotechnology Systems, Inc.
Current Status: Cyberkinetics is no longer in business.
Company Profile: Cyberkinetics Neurotechnology Systems was a medical device company developing products to treat neurological diseases and injuries involving the spinal cord and peripheral nerves. The company utilized electrical stimulation technologies for nerve growth and neural implants combined a with signal processing apparatus that accessed and interacted with the cerebral cortex and motor cortex at the individual cell level.
Affiliation to Emory: Donald Humphrey, PhD (physiology) is an inventor.
Cylerus Corp.
Current Status: Cylerus is no longer in business.
Company Profile: Cylerus was a start-up company that developed technological improvements in order to enable uniform, localized drug delivery. To allow for the preservation of the functions of artificial blood vessels (vascular grafts). These advances were to address the medical need to prevent vascular graft failure that currently results from localized blood clotting and abnormal tissue in-growth within such grafts. The goal was to minimize the side effects associated with other drug delivery systems used for these applications.
Affiliation to Emory: Stephen Hanson, PhD (cardiology) was a scientific founder and inventor.
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D
Dr. Noze Best
Address: 209 Oak Ln, Decatur, GA 30030
Dr. Noze Best website
President & CEO: Steven Goudy
Current Status: Products on the market
Company Profile: Dr. Noze Best (formerly known as BeeClear) is a company focused on providing a nasal suction device for children that is ergonomic, efficient, and hygienic. The Dr. Noze Best device provides advantages such as a novel ergonomic design that offers more control for the parents, and inherently more safety for the child. Unlike other devices, the NozeBot® Electric Nasal Aspirator device allows parents to stabilize the child with both hands.
Affiliation with Emory: Steven Goudy, MD (pediatrics) is the scientific founder.
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EMRGE, LLC
Address: 425 Framl;om Gatewau SE. Siote 560, Marietta, GA 30067
BRIJ Medical website
CEO: Tim Gleeson
Current Status: Products on the market
Company Profile: BRIJ Medical (formerly EMRGE) was founded to focus on the areas of wound closure, scar reduction, and enhanced application of adhesive backed devices. Brijjit is focused on force modulating tissue bridges to reduce tension on a healing skin wound to improve blood supply and healing.
Affiliation to Emory: Felmont Eaves III, MD (surgery) is the scientific founder of the company.
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Focused Cryo
Address: 2025 Barrett Lake Blvd #2307, Kennesaw, GA 30144
President: Yogi Patel
Current Status: In prototype development and pre-clinical studies
Company Profile: Clinical studies have demonstrated that chronic pain can be treated by interrupting specific nerve pathways at specific locations. Focused Cryo's work has demonstrated that cryoablation is a superior tool for ablating peripheral nerves. Unlike other modalities of modulating or ablating nerves, cryoablation does not burn away tissue but rather induces a controlled biological response that leads to a breakdown and subsequent resetting of the diseased pathway. What is desired is a system that enables targeted, spatially-controllable, and precise nerve cryoablation. Focused Cryo is developing an easy to use, customizable, and smart cryoablation system that provides precise guidance, targeting, and controlled cryoablation of nerves.
Affiliation with Emory: David Prologo MD (radiology & imaging sciences) is the scientific founder.
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Innovative Cardiac Technologies, LLC (ICT)
Address: 5231 Powers Ferry Road, Atlanta, GA 30327
CEO: James G. Tausche
Current Status: Products on the market
Company Profile: Innovative Cardiac Technologies, LLC (ICT) is devices used in cardiac and other surgical procedures.
Affiliation with Emory: John D. Puskas, MD (surgery) is an inventor.
Interventional Innovations Corp. (IIC)
Current Status: IIC is no longer in business.
Company Profile: Interventional Innovations were targeting restenosis with a minimally invasive catheter-based x-ray therapy which uses soft, or less energized x-rays. Interventional's system consisted of an x-ray catheter, a delivery sheath and a control unit that allows the physician to increase the depth of penetration, making it possible to tailor the radiation to treat a variety of disease states.
Affiliation with Emory: Stephen Hanson, PhD, (cardiology) Laurence Harker, MD, (hematology & medical oncology) Spencer King III, MD, (cardiology) and Neal Scott, MD (cardiology) are inventors.
iMacular Regeneration, LLC
Address: 211 First Avenue SW, Suite 202, Rochester, MN 55902
CEO: Timothy Olsen
Current Status: In preclinical development
Company Profile: iMacular Regeneration is developing a novel tissue support structure (macular O-rings or MORs), made from a biocompatible, implantable material (nitinol or nickel-titanium alloy) to address the treatment of advanced age-related macular degeneration. The device supports and protects donor tissue, reconstruct the degenerating tissue in the submacular space, enables translocation of autographs, and/or potentially other transplants or three-dimensional tissue organoids into the submacular space. MORs provide a biocompatible perimeter scaffold. Thus, the MORs facilitate surgical manipulation and minimize tissue injury for the delicate, three-dimensional, choroid-Bruch's-RPE (CBR) tissue transplants used in translocation surgery.
Affiliation with Emory: Timothy Olsen, MD (ophthalmology) is the scientific founder.
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Medluminal Systems, Inc.
Address: 2454 Embarcadero Way, Palo Alto, CA 94303
Director: Michael B. Sweeney
Current Status: In the developmental phase
Company Profile: Medluminal Systems (formerly Radiovascular Systems) manufactures catheters for angioplasty to improve the success rate of surgeries. The company is focused on working in the field of vascular brachytherapy, which is the use of intravascular radiation in order to reduce the incidence of re-stenosis. Medluminal has developed a unique catheter that could significantly improve the success rate of angioplasty procedures in coronary and peripheral arteries.
Affiliation with Emory: Neal Scott, MD, (cardiology) is one of the founders.
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Neotonus, Inc.
Current Status: Neotonus is no longer in business.
Company Profile: Neotonus, Inc. focused on non-invasive healthcare solutions for the treatment of neuromuscular disorders. Its products were the NeoControl pelvic floor therapy system, which was used in urology, obstetrics/gynecology, and physical therapy practices.
Affiliation with Emory: Charles Epstein, MD (neurology) is an inventor.
Neuronetics, Inc.
Address: 31 General Warren Blvd., Malvern, PA 19355-1245
Neuronetics website
President and CEO: Michael D. Dale
Current Status: Products on the market
Company Profile: Neuronetics develops non-invasive therapies for psychiatric and neurological disorders. Neuronetics developed the NeuroStar® system, which uses transcranial magnetic stimulation TMS therapy, a non-invasive form of neuro-modulation utilizing a magnetic coil design. Therapy is delivered under the supervision of a psychiatrist during an out-patient procedure.
Affiliation with Emory: Charles Epstein, MD (neurology) is an inventor.
Neuropace, Inc.
Current Status: Neuropace no longer has a license to Emory technology.
Company Profile: NeuroPace was focused on implantable devices for the treatment of neurological disorders by responsive brain stimulation. The initial focus was the treatment of epilepsy. The system contained a battery pack, a microprocessor, and a series of electrodes implanted near the focus of the epileptic seizures. When the microprocessor senses the onset of a seizure, it quickly delivers a small series of pulses to stop the seizure. The electrical impulses act to desynchronize a group of neurons that are beginning to show synchronized activity, which eventually cause a seizure.
Affiliation to Emory: Brian Litt, MD, (neurology) is an inventor.
NiPro, LLC
Address: 111 N Main St, Hecker, IL 62248
CEO: Matt Heck
Current Status: In prototype development and validation
Company Profile: NiPro is developing nipple implant systems for breast cancer survivors which utilizes a prostheses rather than undergoing an additional operation. Many breast cancer survivors will add some sort of permanent or semi-permanent nipple appearance either through 3D tattoos or reconstructed nipples. NiPro is developing a novel prosthetic nipple anchoring device system as a potential solution to the physical and emotional void associated with the effects of mastectomies. The device is an anchor that interfaces with patented exterior prosthetic nipples and cosmetics which provides a simple long-term, cosmetically appealing solution.
Affiliation with Emory: Nicholas Boulis, MD, (neurosurgery) and Saumya Gurbani (neurosurgery) are inventors.
Novoste Corp.
Current Status: Novoste was purchased by Best Vascular in 2006. Novoste no longer has a license to Emory technology.
Company Profile: Novoste Corporation developed advanced medical treatments for coronary and vascular diseases. The Beta-Cath System, is primarily used to treat patients suffering from "in-stent" restenosis, a condition where coronary stents become blocked with new tissue growth. The Beta-Cath system uses vascular brachytherapy to prevent the artery from reclosing during a procedure.
Affiliation to Emory: Ian Crocker, MD, (hematology and radiology) Spencer King, MD, (cardiology) Keith Robinson, PhD, (cardiology) and Ron Waksman, MD, (cardiology) are inventors.
Nyra Medical, Inc.
Address: 2459 Oak Grove Heights, Decatur, GA 30033
Nyra Medical website
CEO: Lori Chmura
Current Status: In preclinical testing
Company Profile: Nyra Medical is developing a transcatheter cardiac valve leaflet enhancer (CARLEN) technology to repair leaky heart valves using image-guided catheters in place of traditional open-heart surgery. Traditionally, a valve leak is managed with medications by altering the hemodynamics, or in some patients with risky, open-heart surgery. The CARLEN technology is designed to repair leaky valves by deploying a miniature implant onto the valve that extends its dimensions, at the end of a thin, image-guided, catheter.
Affiliation with Emory: Muralidhar Padala, PhD (surgery) is a co-founder.
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Revitus, Inc.
Current Status: Revitus merged with BioVascular in 2007. Revitus no longer has a license to the Emory technology.
Company Profile: Revitus produced products designed to produce pharmacological treatment for prevention of thrombotic vascular disorders. It offered a drug to prevent heart attack and stroke.
Affiliation to Emory: Stephen Hanson, PhD (cardiology) is an inventor.
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Spectropath, Inc.
Current Status: Spectropath is no longer in business.
Company Profile: Spectropath provided an optical and electronic interface for oncological surgeons to see cancer malignancies. If a piece of malignancy remains, further surgery or chemotherapy may be needed to eradicate the cancer in the patient. Spectropaths quantum dot technology visualized tissue that is malignant for the surgeon to see in real-time.
Affiliation with Emory: Shuming Nie, PhD, (hematology & oncology and biomedical engineering) is an inventor.
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TendoNova Corporation
Address: 1161 The By Way NE, Atlanta, GA 30306
TendoNova website
CEO: Mark Samuels
Current Status: Products on the market
Company Profile: Tendinopathy is a chronic disease state that is a result of repetitive trauma leading to a static cellular state. This leaves the tendon containing disorganized collagen fibers, capillaries, and nerves leading to pain and disability. Percutaneous needle tenotomy (PNT) is a procedure where the tendon is repeatedly punctured with a needle, resulting in fenestration of unhealthy tissue. This microtrauma helps restart the healing cycle promoting new, healthy tissue to form. Tendonova developed the Ocelot™ system, to allow for more effective and efficient percutaneous needle tenotomies in a doctors office and lowered the cost.
Affiliation with Emory: Kenneth Mautner, MD (orthopaedics) is an inventor.
TransCardiac Therapeutics, LLC (TCT)
Current Status: TransCardiac Therapeutics is no longer in business.
Company Profile: TransCardiac Therapeutics (TCT) developed a device that allowed easy access and safe delivery of therapeutics to the inside or outside of a heart, while it is still beating. In addition, TCT had technology in repairing heart valves.
Affiliation with Emory: Omar Lattouf, MD, PhD (surgery) is an inventor.
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Visufy, Inc.
Address: 3951 White Horse Lane SE, Smyrna, GA 30080
CEO: Yousuf Khalifa
Current Status: In product development
Company Profile: The company is developing a multi-purpose ocular monitoring headset.
Affiliation with Emory: Yousuf Khalifa, MD (ophthalmology) is an inventor.
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Zenda Technologies
Current Status: Zenda is no longer in business.
Company Profile: Zenda Technologies was developing products for fast, accurate neuropsychological assessments. The company's first tests on the licensed platform (DETECT) was to assess cognitive function for mild traumatic brain injury (mTBI) associated with concussion and for mild cognitive impairment, (MCI) which is a symptom of early Alzheimer's disease.
Affiliation with Emory: Michelle LaPlaca, PhD (biomedical engineering) and David Wright, MD, (emergency medicine) are inventors.